Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: NDC80
Gene Name: NDC80
Protein Full Name: Kinetochore protein NDC80 homolog
Alias: HEC; Highly expressed in cancer, rich in leucine heptad repeats; Kinetochore associated 2; KNTC2; NDC80, kinetochore complex component; Retinoblastoma-associated protein HEC; TID3
Mass (Da): 73913
Number AA: 642
UniProt ID: O14777
Locus ID: 10403
COSMIC ID: NDC80
Gene location on chromosome: 18p11.32
Cancer protein type: NA
Effect of cancer mutation on protein: NA
Effect of active protein on cancer: NA
Number of cancer specimens: 19625
Percent of cancer specimens with mutations: 0.48
Normal role description: NA


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