Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: TP73
Gene Name: TP73
Protein Full Name: Tumor protein p73
Alias: p53-like transcription factor; p53-related protein; P73; P73 alpha protein; p73-alpha; TP73; TRP73
Mass (Da): 69623
Number AA: 636
UniProt ID: O15350; C9J521
Locus ID: 7161
COSMIC ID: TP73
Gene location on chromosome: 1p36.3; 1p36.32
Number of cancer specimens: 19907
Percent of cancer specimens with mutations: 0.48
Gene undergoes hypermethylation: Diverse tumours
Normal role description: Aids p53 to trigger apoptosis.


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