Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: ACTN4
Gene Name: ACTN4
Protein Full Name: Alpha-actinin-4
Alias: AAC4; actinin, alpha 4; Alpha-actinin 4; F-actin cross linking protein; Non-muscle alpha-actinin 4
Mass (Da): 104854
Number AA: 911
UniProt ID: O43707
Locus ID: 81
COSMIC ID: ACTN4
Gene location on chromosome: 19q13.2
Number of cancer specimens: 19625
Percent of cancer specimens with mutations: 0.71


Provide the gene name, protein name, UniProt ID or Locus ID as a search term. Click on Retrieve Info button to obtain information on the selected cancer protein.