Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: SPAG9
Gene Name: SPAG9
Protein Full Name: C-Jun-amino-terminal kinase-interacting protein 4
Alias: HSS; JLP; JNK-associated leucine-zipper protein; JNK-interacting protein 4; MAPK8-interacting protein 4; PHET; PIG6; Sunday driver 1
Mass (Da): 146205
Number AA: 1321
UniProt ID: O60271
Locus ID: 9043
COSMIC ID: SPAG9
Gene location on chromosome: 17q21.33
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 20150
Percent of cancer specimens with mutations: 0.87
Normal role description: Organizes MAP kinases and mediates c-Jun-terminal kinase signalling. May be involved in membrane transport and tumour growth and development.


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