Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: HBP1
Gene Name: HBP1
Protein Full Name: HMG box-containing protein 1
Alias: HMG box transcription factor 1;High mobility group box transcription factor 1
Mass (Da): 57645
Number AA: 514
UniProt ID: O60381
Locus ID: 26959
COSMIC ID: HBP1
Gene location on chromosome: 7q22.3
Cancer protein type: TSP
Effect of cancer mutation on protein: LOSS
Effect of active protein on cancer: PROMOTES
Number of cancer specimens: 19625
Percent of cancer specimens with mutations: 0.36
Normal role description: Functions in cell cycle regulation as a cell cycle inhibitor


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