Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: PLCH2
Gene Name: PLCH2
Protein Full Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodie
Alias: Phosphoinositide phospholipase C-like 4; phospholipase C-eta-2; PLC-eta2; PLCH2
Mass (Da): 154668
Number AA: 1416
UniProt ID: O75038
Locus ID: 9651
COSMIC ID: PLCH2
Gene location on chromosome: 1p36.32
Number of cancer specimens: 19717
Percent of cancer specimens with mutations: 0.7
Normal role description: Phospholipase
Commentary on involvement of protein in cancer: no entry in AGO


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