Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ARL6IP5 |
| Gene Name: | ARL6IP5 |
| Protein Full Name: | PRA1 family protein 3 |
| Alias: | ADP-ribosylation factor-like protein 6-interacting protein 5;Cytoskeleton-related vitamin A-responsive protein;Dermal papilla-derived protein 11;GTRAP3-18;Glutamate transporter EAAC1-interacting protein;JM5;Prenylated Rab acceptor protein 2;Protein JWa;Putative MAPK-activating protein PM27 |
| Mass (Da): | 21615 |
| Number AA: | 188 |
| UniProt ID: | O75915 |
| Locus ID: | 10550 |
| COSMIC ID: | ARL6IP5 |
| Gene location on chromosome: | 3p14.1 |
| Number of cancer specimens: | NA |
| Percent of cancer specimens with mutations: | NA |
| Normal role description: | Regulates intracellular concentrations of taurine and glutamate. ARL6IP5 downregulates EAAC1-mediated transport of glutamic acid outside of the cell. Expression of ARL6IP5 increased during treatment of AML with retinoic acid leading to hematopoetic differentiation. |