Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: PIAS1
Gene Name: PIAS1
Protein Full Name: E3 SUMO-protein ligase PIAS1
Alias: AR interacting protein; DDXBP1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; GBP; GU/RH-II; Gu-binding protein; Protein inhibitor of activated STAT protein 1; Protein inhibitor of activated STAT, 1; Protein inhibitor of activated STAT-1; RNA helicase II-binding protein; Zinc finger, MIZ-type containing 3; ZMIZ3
Mass (Da): 71836
Number AA: 651
UniProt ID: O75925
Locus ID: 8554
COSMIC ID: PIAS1
Gene location on chromosome: 15q23
Number of cancer specimens: 20215
Percent of cancer specimens with mutations: 0.34


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