Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: PLEKHG5
Gene Name: PLEKHG5
Protein Full Name: Pleckstrin homology domain-containing family G mem
Alias: Dsma4; Gef720; Guanine nucleotide exchange factor 720; Kiaa0720; Pleckstrin homology domain containing family g member 5; Pleckstrin homology domain containing, family g (with rhogef domain) member 5; Pleckstriny domain containing, family G (with RhoGef domain) member 5; Plekhg5; Rp4-650h14.3
Mass (Da): 117432
Number AA: 1062
UniProt ID: O94827
Locus ID: 57449
COSMIC ID: PLEKHG5
Gene location on chromosome: 1p36.31
Number of cancer specimens: 19718
Percent of cancer specimens with mutations: 0.01
Commentary on involvement of protein in cancer: no entry in AGO


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