Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | NFAT5 |
| Gene Name: | NFAT5 |
| Protein Full Name: | Nuclear factor of activated T-cells 5 |
| Alias: | KIAA0827; NF-AT5; NFATL1; NFATZ; nuclear factor of activated T cells 5; nuclear factor of activated T-cells 5, tonicity-responsive; OREBP; T cell transcription factor NFAT5; TonE-binding protein; TonEBP; tonicity-responsive enhancer-binding protein |
| Mass (Da): | 165763 |
| Number AA: | 1531 |
| UniProt ID: | O94916 |
| Locus ID: | 10725 |
| COSMIC ID: | NFAT5 |
| Gene location on chromosome: | 16q22.1 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.87 |
| Commentary on involvement of protein in cancer: | Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes. |