Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | KCNH1 |
| Gene Name: | KCNH1 |
| Protein Full Name: | Potassium voltage-gated channel subfamily H member |
| Alias: | Ether-a-go-go potassium channel 1;Voltage-gated potassium channel subunit Kv10.1 |
| Mass (Da): | 111423 |
| Number AA: | 989 |
| UniProt ID: | O95259 |
| Locus ID: | 3756 |
| COSMIC ID: | KCNH1 |
| Gene location on chromosome: | 1q32.2 |
| Cancer protein type: | OP |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | PROMOTES |
| Number of cancer specimens: | 19628 |
| Percent of cancer specimens with mutations: | 1.54 |
| Normal role description: | Usually expressed almost exclusively in brain tissue but has been routinely found upregulated in a wide variety of tumors; may confer them growth advantage. |