Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: LPHN2
Gene Name: LPHN2
Protein Full Name: Latrophilin-2
Alias: Calcium-independent alpha-latrotoxin receptor 2; KIAA0786; Latrophilin 2; Latrophilin homolog 1; LEC1; Lectomedin-1; LPHH1
Mass (Da): 163349
Number AA: 1459
UniProt ID: O95490; Q9UJ48; Q9UJ49; Q9UJ50; Q9UJ51; Q9UJ52;
Locus ID: 23266
COSMIC ID: LPHN2
Gene location on chromosome: 1p31.1
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 20103
Percent of cancer specimens with mutations: 1.9
Normal role description: Receptor - G protein-coupled, 7TM.


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