Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: ACSL3
Gene Name: ACSL3
Protein Full Name: Long-chain-fatty-acid--CoA ligase 3
Alias: ACS3; Acyl-CoA synthetase long-chain family member 3; FACL3; LACS 3; LACS3; LCF3; Long-chain acyl-CoA synthetase 3; PRO2194
Mass (Da): 80420
Number AA: 720
UniProt ID: O95573
Locus ID: 2181
COSMIC ID: ACSL3
Gene location on chromosome: 2q36.1
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 19805
Percent of cancer specimens with mutations: 0.41
Normal role description: Lipid Metabolism - fatty acid; Ligase


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