Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: AGR2
Gene Name: AGR2
Protein Full Name: Anterior gradient protein 2 homolog
Alias: HPC8;Secreted cement gland protein XAG-2 homolog
Mass (Da): 19979
Number AA: 175
UniProt ID: O95994
Locus ID: 10551
COSMIC ID: AGR2
Gene location on chromosome: 7p21.3*
Cancer protein type: NA
Effect of cancer mutation on protein: NA
Effect of active protein on cancer: NA
Number of cancer specimens: 20057
Percent of cancer specimens with mutations: 0.12
Normal role description: NA
Commentary on involvement of protein in cancer: *Note; According to Atlas of Gene Oncology, the gene is located on chromosome 7p21.1 and not 7p21.3.


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