Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: Fos
Gene Name: FOS
Protein Full Name: Proto-oncogene c-Fos
Alias: Cellular oncogene fos
Mass (Da): 40695
Number AA: 380
UniProt ID: P01100
Locus ID: 2353
COSMIC ID: FOS
Gene location on chromosome: 14q24.3
Cancer protein type: OP
Effect of cancer mutation on protein: GAIN
Effect of active protein on cancer: PROMOTES
Number of cancer specimens: 20338
Percent of cancer specimens with mutations: 0.28
Normal role description: Transcription protein for API


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