Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | TGFA |
| Gene Name: | TGFA |
| Protein Full Name: | Protransforming growth factor alpha |
| Alias: | EGF-like TGF;TGF type 1 |
| Mass (Da): | 17006 |
| Number AA: | 160 |
| UniProt ID: | P01135; Q9UIS1; Q9UIS2; Q9UIS3; Q9UKM3 |
| Locus ID: | 7039 |
| COSMIC ID: | TGFA |
| Gene location on chromosome: | 2p13 |
| Number of cancer specimens: | 20233 |
| Percent of cancer specimens with mutations: | 0.19 |
| Normal role description: | TGF-alpha acts as an autocrine growth factor in squamous cell lung, breast and prostate adenocarcinomas, pancreatic cancers and mesotheliomas. |