Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | PIGR |
| Gene Name: | PIGR |
| Protein Full Name: | Polymeric immunoglobulin receptor |
| Alias: | Hepatocellular carcinoma-associated protein TB6; Poly-Ig receptor; Polymeric immunoglobulin receptor; Polymeric-immunoglobulin receptor |
| Mass (Da): | 83284 |
| Number AA: | 764 |
| UniProt ID: | P01833 |
| Locus ID: | 5284 |
| COSMIC ID: | PIGR |
| Gene location on chromosome: | 1q32.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19626 |
| Percent of cancer specimens with mutations: | 0.86 |
| Normal role description: | PIGR codes a receptor that binds to IgA and IgM on the basolateral side of a cell. Upon binding, the complex is transported across the membrane to the apical surface and secreted. |