Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: THY1
Gene Name: THY1
Protein Full Name: Thy-1 membrane glycoprotein
Alias: CDw90;Thy-1 antigen
Mass (Da): 17935
Number AA: 161
UniProt ID: P04216
Locus ID: 7070
COSMIC ID: THY1
Gene location on chromosome: 11q23.3
Cancer protein type: TSP
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: INHIBITS
Number of cancer specimens: 19626
Percent of cancer specimens with mutations: 0.16
Normal role description: Membrane glycoprotein. May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Commentary on involvement of protein in cancer: No mutations identified on the Atlas of Oncology, the Sanger COSMIC database or Uniprot.


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