Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: CD74
Gene Name: CD74
Protein Full Name: HLA class II histocompatibility antigen gamma chai
Alias: CD74 molecule, major histocompatibility complex, class II invariant chain; DHLAG; Gamma chain of class II antigens; HG2A; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; Ia antigen-associated invariant chain; Ia-associated invariant chain; Ii; MHC HLA-DR gamma chain; P33
Mass (Da): 33516
Number AA: 296
UniProt ID: P04233
Locus ID: 972
COSMIC ID: CD74
Gene location on chromosome: 5q32
Number of cancer specimens: 21730
Percent of cancer specimens with mutations: 0.12


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