Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | NGFR |
| Gene Name: | NGFR |
| Protein Full Name: | Tumor necrosis factor receptor superfamily member |
| Alias: | CD271; Gp80-LNGFR; Low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; Nerve growth factor receptor; NGF receptor; P75 ICD; P75NTR; TNFR superfamily, member 16; TNFRSF16; TNR16; Tumor necrosis factor receptor superfamily member 16 |
| Mass (Da): | 45183 |
| Number AA: | 427 |
| UniProt ID: | P04629 |
| Locus ID: | 4804 |
| COSMIC ID: | NGFR |
| Gene location on chromosome: | 17q21.33 |
| Number of cancer specimens: | 20057 |
| Percent of cancer specimens with mutations: | 0.46 |
| Normal role description: | NGFR is a receptor-tyrosine kinase that is activated upon binding nerve growth factor. |