Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: HMGB1
Gene Name: HMGB1
Protein Full Name: High mobility group protein B1
Alias: Amphoterin; DKFZp686A04236; High mobility group box 1; High mobility group protein 1; High-mobility group box 1; HMG1; HMG-1; HMG3; SBP-1; Sulfoglucuronyl carbohydrate binding protein; Sulfoglucuronyl carbohydrate binding protein high-mobility group (nonhistone chromosomal) protein 1
Mass (Da): 24894
Number AA: 215
UniProt ID: P09429
Locus ID: 3146
COSMIC ID: HMGB1
Gene location on chromosome: 13q12.3
Number of cancer specimens: 19718
Percent of cancer specimens with mutations: 0.15


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