Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | WNT2 |
| Gene Name: | WNT2 |
| Protein Full Name: | Protein Wnt-2 |
| Alias: | Int-1-like protein 1;Int-1-related protein |
| Mass (Da): | 40418 |
| Number AA: | 360 |
| UniProt ID: | P09544 |
| Locus ID: | 7472 |
| COSMIC ID: | WNT2 |
| Gene location on chromosome: | 7q31.2 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 20120 |
| Percent of cancer specimens with mutations: | 0.55 |
| Normal role description: | Member of the WNT family of secreted signalling molecules, that are implicated in developmental processes, regulation of cell fate, patterning during embryogenesis and oncogenesis. Ligand for members of the frizzled family of seven transmembrane receptors. May be associated with abnormal proliferation in breast tissue. |