Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | RAP2A |
| Gene Name: | RAP2A |
| Protein Full Name: | Ras-related protein Rap-2a |
| Alias: | RbBP-30 |
| Mass (Da): | 20615 |
| Number AA: | 183 |
| UniProt ID: | P10114 |
| Locus ID: | 5911 |
| COSMIC ID: | RAP2A |
| Gene location on chromosome: | 13q34 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 20339 |
| Percent of cancer specimens with mutations: | 0.16 |
| Normal role description: | Active form interacts with and regulates several effectors (such as MAP4K4, MINK1 and TNIK). Involved in several signalling cascades. Suggested to be involved in cytoskeletal rearrangements, cell migration and adhesion as well as cell spreading. |