Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: CYP2D6
Gene Name: CYP2D6
Protein Full Name: Cytochrome P450 2D6
Alias: CP2D6; CPD6; CYP2D; CYP2D@; CYP2DL1; CYPIID6; Cytochrome P450, family 2, subfamily D, polypeptide 6; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase; P450C2D; P450-DB1
Mass (Da): 55751
Number AA: 497
UniProt ID: P10635
Locus ID: 1565
COSMIC ID: CYP2D6
Gene location on chromosome: 22q13.2
Number of cancer specimens: 19670
Percent of cancer specimens with mutations: 0.43


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