Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | HSPD1 |
| Gene Name: | HSPD1 |
| Protein Full Name: | 60 kDa heat shock protein, mitochondrial |
| Alias: | 60 kDa chaperonin; CH60; CPN60; Heat shock protein 60; HSP-60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein |
| Mass (Da): | 61055 |
| Number AA: | 573 |
| UniProt ID: | P10809 |
| Locus ID: | 3329 |
| COSMIC ID: | HSPD1 |
| Gene location on chromosome: | 2q33.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19717 |
| Percent of cancer specimens with mutations: | 0.55 |
| Normal role description: | HSPD1 is a mitochondrial chaperon protein. It is involved in mitochondiral protein folding, unfolding and degradation. It also has pro- and anti-apoptotic roles. It may also have a signalling role in the innate immune system. |