Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: RARB
Gene Name: RARB
Protein Full Name: Retinoic acid receptor beta
Alias: HBV-activated protein; Nuclear receptor 1B2; RAR-beta; RAR-epsilon
Mass (Da): 50489
Number AA: 455
UniProt ID: P10826
Locus ID: 5915
COSMIC ID: RARB
Gene location on chromosome: 3p24.2
Number of cancer specimens: 20400
Percent of cancer specimens with mutations: 0.47
Gene undergoes hypermethylation: Breast and lung tumours.
Normal role description: Receptor-nuclear. For differentiation.


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