Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: THRA
Gene Name: THRA
Protein Full Name: Thyroid hormone receptor alpha
Alias: AR7; C-erbA-1; C-erbA-alpha; EAR7; EAR-7; EAR-7.1/EAR-7.2; ERBA; ERBA1; Erythroblastic leukemia viral (v-erb-a) oncogene; NR1A1; THA; THRA1; THRA2; THRA3; Thyroid hormone receptor, alpha; TR-alpha-2
Mass (Da): 54816
Number AA: 490
UniProt ID: P10827
Locus ID: 7067
COSMIC ID: THRA
Gene location on chromosome: 17q21.1
Number of cancer specimens: 19719
Percent of cancer specimens with mutations: 0.39
Transduced into viral genome: Avian erythroblastosis ES4 virus - Chicken
Normal role description: Receptor for thyroid hormone.


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