Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CD79A |
| Gene Name: | CD79A |
| Protein Full Name: | B-cell antigen receptor complex-associated protein |
| Alias: | CD79A; CD79a molecule, immunoglobulin-associated alpha; IGA; MB1; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin associated protein; Surface-IGM- associated protein; Surface-IgM- associated protein |
| Mass (Da): | 25038 |
| Number AA: | 226 |
| UniProt ID: | P11912 |
| Locus ID: | 973 |
| COSMIC ID: | CD79A |
| Gene location on chromosome: | 19q13.2 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 20581 |
| Percent of cancer specimens with mutations: | 0.32 |
| Normal role description: | Part of the B cell antigen receptor. Essential for BCR surface expression and efficient differentiation of pro- and pre-B-cells. Represses BCR signalling during development of immature B cells |