Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | MYH1 |
| Gene Name: | MYH1 |
| Protein Full Name: | Myosin-1 |
| Alias: | MGC133384; MYHa; MyHC-2X/D; MyHC-IIx/d; MYHSA1; Myosin heavy chain 1; Myosin heavy chain 2x; Myosin heavy chain IIx/d; Myosin heavy chain, skeletal muscle, adult 1; Myosin, heavy chain 1, skeletal muscle, adult |
| Mass (Da): | 223145 |
| Number AA: | 1939 |
| UniProt ID: | P12882 |
| Locus ID: | 4619 |
| COSMIC ID: | MYH1 |
| Gene location on chromosome: | 17p13.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19811 |
| Percent of cancer specimens with mutations: | 3.01 |
| General distribution of mutations: | Multi-site |
| Location of most mutations: | Broad distribution of mutation sites with point mutations over protein length, but no insertions or deletions. |
| Normal role description: | Involved in muscle contraction. |