Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CEACAM1 |
| Gene Name: | CEACAM1 |
| Protein Full Name: | Carcinoembryonic antigen-related cell adhesion mol |
| Alias: | ATP-dependent taurocolate-carrier protein; BGP; BGP1; BGP-1; BGPD; Biliary glycoprotein; Biliary glycoprotein 1; Biliary glycoprotein D; Carcinoembryonic antigen-related cell adhesion molecule 1; CBATP; C-CAM 105; CD66; CD66a; CEAM1; Cell-CAM 105; Ecto-ATPase; GP110; HA4 |
| Mass (Da): | 57560 |
| Number AA: | 526 |
| UniProt ID: | P13688 |
| Locus ID: | 634 |
| COSMIC ID: | CEACAM1 |
| Gene location on chromosome: | 19q13.2 |
| Cancer protein type: | TSP/OP |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | MIXED |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.45 |
| Normal role description: | The role of CEACAM1 is diverse and its involvement in tumorigenesis complex. It promotes tumour angiogenesis, cellular migration of blood vessel endothelial cells, promotes or inhibits apoptosis in different tissues. Involved in differentiation and modulation of immune responses. In different cancers up- or downregulated. |