Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | IL2RB |
| Gene Name: | IL2RB |
| Protein Full Name: | Interleukin-2 receptor subunit beta |
| Alias: | CD122; CD122 antigen; High affinity IL-2 receptor beta subunit; IL-2 receptor; IL-2R beta; Interleukin 2 receptor, beta; Interleukin-2 receptor beta chain precursor; P70-75 |
| Mass (Da): | 61117 |
| Number AA: | 551 |
| UniProt ID: | P14784 |
| Locus ID: | 3560 |
| COSMIC ID: | IL2RB |
| Gene location on chromosome: | 22q12.3 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.54 |
| Normal role description: | Receptor - for cytokine interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. |