Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: CDH2
Gene Name: CDH2
Protein Full Name: Cadherin-2
Alias: CADH2; Cadherin 2, type 1, N-cadherin (neuronal); Cadherin, neural; Cadherin-2; CD325; CDHN; CDw325; NCAD; N-cad; N-cadherin; Neural-cadherin
Mass (Da): 99809
Number AA: 906
UniProt ID: P19022
Locus ID: 1000
COSMIC ID: CDH2
Gene location on chromosome: 18q12.1
Number of cancer specimens: 20117
Percent of cancer specimens with mutations: 1.35
Normal role description: Calcium dependent cell-cell adehesion glycoprotein.


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