Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CD53 |
| Gene Name: | CD53 |
| Protein Full Name: | Leukocyte surface antigen CD53 |
| Alias: | Cell surface glycoprotein CD53;Tetraspanin-25 |
| Mass (Da): | 24341 |
| Number AA: | 219 |
| UniProt ID: | P19397 |
| Locus ID: | 963 |
| COSMIC ID: | CD53 |
| Gene location on chromosome: | 1p13.3 |
| Cancer protein type: | OP |
| Effect of cancer mutation on protein: | GAIN |
| Effect of active protein on cancer: | PROMOTES |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.3 |
| Normal role description: | May be involved in growth regulation in hematopoietic cells. It can complex with integrins and CD2. It is involved in signal transduction resulting in cell development, actiavtion, growth and motility. |