Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CXCL2 |
| Gene Name: | CXCL2 |
| Protein Full Name: | C-X-C motif chemokine 2 |
| Alias: | Growth-regulated protein beta;Macrophage inflammatory protein 2-alpha;GRO-beta-T;Hematopoietic synergistic factor;SB-251353 |
| Mass (Da): | 11389 |
| Number AA: | 107 |
| UniProt ID: | P19875 |
| Locus ID: | 2920 |
| COSMIC ID: | CXCL2 |
| Gene location on chromosome: | 4q13.3 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.06 |
| Normal role description: | Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. |