Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ITGAX |
| Gene Name: | ITGAX |
| Protein Full Name: | Integrin alpha-X |
| Alias: | CD11 antigen-like family member C;Leu M5;Leukocyte adhesion glycoprotein p150,95 alpha chain;Leukocyte adhesion receptor p150,95 |
| Mass (Da): | 127829 |
| Number AA: | 1163 |
| UniProt ID: | P20702 |
| Locus ID: | 3687 |
| COSMIC ID: | ITGAX |
| Gene location on chromosome: | 16p11.2 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19717 |
| Percent of cancer specimens with mutations: | 1.68 |
| Normal role description: | leukocyte specific intergrin and mediates adherence of neutrophils and monocytes to stimilated endothelium and phagocytosis of complement aoated particles |