Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CD9 |
| Gene Name: | CD9 |
| Protein Full Name: | CD9 antigen |
| Alias: | 5H9 antigen;Cell growth-inhibiting gene 2 protein;Leukocyte antigen MIC3;Motility-related protein;Tetraspanin-29;p24 |
| Mass (Da): | 25416 |
| Number AA: | 228 |
| UniProt ID: | P21926 |
| Locus ID: | 928 |
| COSMIC ID: | CD9 |
| Gene location on chromosome: | 12p13.31 |
| Cancer protein type: | TSP |
| Effect of cancer mutation on protein: | LOSS |
| Effect of active protein on cancer: | MIXED |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.2 |
| Normal role description: | CD9 is a cell surface protein part of tetraspanin family. It is involved in differentiation, platelet activation and aggregation, adhesion, motility and signal transduction. Dysregulation can give cancer progress an advantage or disadvantage. |