Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | S100P |
| Gene Name: | S100P |
| Protein Full Name: | Protein S100-P |
| Alias: | Protein S100-E;S100 calcium-binding protein P |
| Mass (Da): | 10400 |
| Number AA: | 95 |
| UniProt ID: | P25815 |
| Locus ID: | 6286 |
| COSMIC ID: | S100P |
| Gene location on chromosome: | 4p16.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.08 |
| Mutations observed as inherited: | NA |
| Found in amplified chromosomal regions in human cancers: | NA |
| Deregulated in translocations: | NA |
| Deregulated by viral insertion: | NA |
| Transduced into viral genome: | NA |
| Gene undergoes hypermethylation: | NA |
| Normal role description: | S100P is a calcium-binding protein that may be involved in regulating cell cycle progression and differentiation. There is evidence suggesting that it may play a role in prostate cancer etiology - it has been shown to be upregulated in pancreatic cancer cell lines. Its exact functions is still largely unknown. |