Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | ZFP36 |
| Gene Name: | ZFP36 |
| Protein Full Name: | Tristetraprolin |
| Alias: | G0/G1 switch regulatory protein 24; G0S24; Growth factor-inducible nuclear protein NUP475; NUP475; RNF162A; TIS11; TIS11A; TIS11A protein; Tristetraprolin; Zfp-36; Zinc finger protein 36 homolog; Zinc finger protein 36, C3H type, |
| Mass (Da): | 34003 |
| Number AA: | 326 |
| UniProt ID: | P26651 |
| Locus ID: | 7538 |
| COSMIC ID: | ZFP36 |
| Gene location on chromosome: | 19q13.2 |
| Number of cancer specimens: | 19717 |
| Percent of cancer specimens with mutations: | 0.25 |
| Normal role description: | Regulatory nuclear protein. Probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Has been experimentally shown to be able to bind zinc. |