Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: PTPN6
Gene Name: PTPN6
Protein Full Name: Tyrosine-protein phosphatase non-receptor type 6
Alias: 70Z-SHP; EC 3.1.3.48; HCP; HCPH; PTN6; PTP1C; SH-PTP1
Mass (Da): 67561
Number AA: 595
UniProt ID: P29350
Locus ID: 5777
COSMIC ID: PTPN6
Gene location on chromosome: 12p13.31
Number of cancer specimens: 20347
Percent of cancer specimens with mutations: 0.46
Normal role description: PTPN6 is a protein-tyrosine phosphatase.


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