Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Protein Name: | RBMS1 |
Gene Name: | RBMS1 |
Protein Full Name: | RNA-binding motif, single-stranded-interacting pro |
Alias: | C2orf12; C-myc gene single strand binding 2; C-Myc gene single strand binding 2; C-myc gene single strand binding protein 2; DKFZp564H0764; HCC-4; MSSP; MSSP1; MSSP-1; MSSP-2; MSSP-3; RNA binding motif, single stranded interacting 1; RNA binding motif, single stranded interacting protein 1; SCR2; Single-stranded DNA-binding MSSP-1; Suppressor of cdc 2 (cdc13) with RNA binding motif 2; Suppressor of CDC2 with RNA- binding motif 2; YC1 |
Mass (Da): | 44505 |
Number AA: | 406 |
UniProt ID: | P29558 |
Locus ID: | 5937 |
COSMIC ID: | RBMS1 |
Gene location on chromosome: | 2q24.2 |
Number of cancer specimens: | 19557 |
Percent of cancer specimens with mutations: | 0.26 |
Commentary on involvement of protein in cancer: | Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. |