Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: PPP2R1B
Gene Name: PPP2R1B
Protein Full Name: Serine/threonine-protein phosphatase 2A 65 kDa reg
Alias: PP2A, subunit A, PR65-beta isoform
Mass (Da): 66196
Number AA: 601
UniProt ID: P30154
Locus ID: 5519
COSMIC ID: PPP2R1B
Gene location on chromosome: 11q23.2
Number of cancer specimens: 20149
Percent of cancer specimens with mutations: 0.37
Normal role description: PPP2R1B is a protein-serine/threonine phosphatase regulatory protein.


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