Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | SRI |
| Gene Name: | SRI |
| Protein Full Name: | Sorcin |
| Alias: | 22 kDa protein;CP-22;V19 |
| Mass (Da): | 21676 |
| Number AA: | 198 |
| UniProt ID: | P30626 |
| Locus ID: | 6717 |
| COSMIC ID: | SRI |
| Gene location on chromosome: | 7q21.12 |
| Number of cancer specimens: | 19626 |
| Percent of cancer specimens with mutations: | 0.14 |
| Normal role description: | Regulatory protein - for RYR2 calcium channels. Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels. |