Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | GSTT1 |
| Gene Name: | GSTT1 |
| Protein Full Name: | Glutathione S-transferase theta-1 |
| Alias: | GST class-theta-1;Glutathione transferase T1-1 |
| Mass (Da): | 27335 |
| Number AA: | 240 |
| UniProt ID: | P30711 |
| Locus ID: | 2952 |
| COSMIC ID: | GSTT1 |
| Gene location on chromosome: | 22q11.23 |
| Number of cancer specimens: | 7055 |
| Percent of cancer specimens with mutations: | 0.17 |
| Normal role description: | Glutathione S-transferase. Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. |