Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CD52 |
| Gene Name: | CD52 |
| Protein Full Name: | CAMPATH-1 antigen |
| Alias: | CDw52;Cambridge pathology 1 antigen;Epididymal secretory protein E5;Human epididymis-specific protein 5 |
| Mass (Da): | 6614 |
| Number AA: | 61 |
| UniProt ID: | P31358 |
| Locus ID: | 1043 |
| COSMIC ID: | CD52 |
| Gene location on chromosome: | 1p36.11 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.06 |
| Normal role description: | GPI-anchored antigen expressed on hematopoietic cells and most lymphoid malignancies. Indetermined whether this overexpression facilitates tumour activity or is functioning as a warning signal to host immune system. Role unclear in normal cells |