Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | MAS1L |
| Gene Name: | MAS1L |
| Protein Full Name: | Mas-related G-protein coupled receptor MRG |
| Alias: | MAS1-like |
| Mass (Da): | 42411 |
| Number AA: | 378 |
| UniProt ID: | P35410; Q502V9; Q5SUN5 |
| Locus ID: | 116511 |
| COSMIC ID: | MAS1L |
| Gene location on chromosome: | 6p22.1* |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 20058 |
| Percent of cancer specimens with mutations: | 0.55 |
| Normal role description: | MAS1L is a GPCR related to the MAS1 oncogene. |
| Commentary on involvement of protein in cancer: | *Located on chromosome 6p21 according to NCBI Gene, and 6p22.1 according to OMIM and Atlas of genetic oncology. 2/134 lung cancer samples were also mutated |