Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | APLNR |
| Gene Name: | APLNR |
| Protein Full Name: | Apelin receptor |
| Alias: | Angiotensin receptor-like 1;G-protein coupled receptor APJ;G-protein coupled receptor HG11 |
| Mass (Da): | 42660 |
| Number AA: | 380 |
| UniProt ID: | P35414 |
| Locus ID: | 187 |
| COSMIC ID: | APLNR |
| Gene location on chromosome: | 11q12.1 |
| Number of cancer specimens: | 20107 |
| Percent of cancer specimens with mutations: | 0.64 |
| Normal role description: | Receptor for apelin and coupled to G proteins that inhibit the adenylate cyclase activity. Functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumour angeogenesis. And also it functions as a HIV-1 coreceptor. |