Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | TIMP3 |
| Gene Name: | TIMP3 |
| Protein Full Name: | Metalloproteinase inhibitor 3 |
| Alias: | metalloproteinase inhibitor 3; MIG-5; SFD; TIMP metallopeptidase inhibitor 3; TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory); TIMP-3; tissue inhibitor of metalloproteinases 3 |
| Mass (Da): | 24140 |
| Number AA: | 211 |
| UniProt ID: | P35625 |
| Locus ID: | 7078 |
| COSMIC ID: | TIMP3 |
| Gene location on chromosome: | 22q12.3 |
| Number of cancer specimens: | 19717 |
| Percent of cancer specimens with mutations: | 0.27 |
| Gene undergoes hypermethylation: | Diverse tumours. |