Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: ACVR1B
Gene Name: ACVR1B
Protein Full Name: Activin receptor type-1B
Alias: Activin A receptor, type IB; Activin receptor-like kinase 4; ActRIB; ACTR-IB; ACV1B; ACVR1B; ACVRLK4; EC 2.7.1.37; EC 2.7.11.30; KIR2; Serine/threonine-protein kinase receptor R2; SKR2
Mass (Da): 56807
Number AA: 505
UniProt ID: P36896
Locus ID: 91
COSMIC ID: ACVR1B
Gene location on chromosome: 12q13
Number of cancer specimens: 1006
Percent of cancer specimens with mutations: 0.89463220676
Normal role description: ACVR1B is a protein-serine/threonine kinase.


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