Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: TGFBR1
Gene Name: TGFBR1
Protein Full Name: TGF-beta receptor type-1
Alias: Activin receptor-like kinase 5; ADRB2; ALK5; EC 2.7.11.30; ESK2; SKR4; TGF-beta receptor type I; TGF-beta type I receptor; TGFR1
Mass (Da): 55960
Number AA: 503
Locus ID: 7046
COSMIC ID: TGFBR1
Number of cancer specimens: 20533
Percent of cancer specimens with mutations: 0.63


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