Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CUX1 |
| Gene Name: | CUX1 |
| Protein Full Name: | Protein CASP |
| Alias: | CUTL1; Homeobox protein cut-like 1 |
| Mass (Da): | 77455 |
| Number AA: | 678 |
| UniProt ID: | P39880 |
| Locus ID: | 1523 |
| COSMIC ID: | CUX1 |
| Gene location on chromosome: | 7q22.1 |
| Number of cancer specimens: | 22556 |
| Percent of cancer specimens with mutations: | 1.37 |
| General distribution of mutations: | Multi-site |
| Location of most mutations: | Broad distribution of mutation sites with some point mutations , but no complex mutations, insertions or deletions. |
| Normal role description: | Regulates gene expression, morphogenesis, differentiation and cell cycle progression. |